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Vomiting or drooling Rapid breathing or panting Increased heart rate Tremors, shaking, or muscle weakness Seizures Diarrhea Pale gums Confusion or agitation Collapse In severe cases, nicotine poisoning can lead to respiratory failure or cardiac arrest

The target quit date should be set within the first 2 weeks of treatment

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Studies have further provided evidence that tobacco smoke can serve as a mutagen and an aneugen of germ cell/spermatozoa (Marchetti et al