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How to treat canker sores on the tongue You can treat canker sores on the tongue by Rinsing your mouth with warm salt water or other gentle over-the-counter mouth rinses a few times every day Practicing proper oral hygiene by brushing with a soft-bristled toothbrush and flossing Drinking enough water every day Limiting how much hot, spicy, and acidic food you have Taking medications your doctor prescribes for the canker sore Canker Sore Home Remedies Home treatments that may help to speed healing and help you feel better include: Topical products