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Those who are eligible to participate must live in one of six geographic locations: Hilo, Hawaii North Hawaii Island Kahului, Maui Molokai Nnkuli-Waianae, Oahu Lhue-Waimea, Kauai Each participant must be 18 years or older, can be a current tobacco smoker, former tobacco smoker, or have never smoked tobacco

Ions that were unassigned, single, and higher than 5-fold charged were excluded from the study

Chuck Negron had been suffering from heart related issues, according to Associated Press

The most common adverse event associated with CHANTIX treatment is nausea, occurring in 30% of patients treated at the recommended dose, compared with 10% in patients taking a comparable placebo regimen [see Warnings and Precautions (5.9)]

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