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Side effects include increased risks for ectopic pregnancy, premature rupture of membranes, abruptio placentae, placenta previa, miscarriage, stillbirth, preterm birth, low birth weight, congenital anomalies like cleft lip, sudden infant death syndrome (SIDS), reduced birth weight, hypertension in the mother, altered fetal development and long-term genetic disorders.

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Repeated episodes are a sign of gastroesophageal reflux disease (GERD)