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It is important for dental practitioners to be aware of oral effects associated with recommended nicotine replacement products, especially when offering smoking cessation advice to patients

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Therefore, we are not proposing to establish an average typical dose different than 100 mg for injectable buprenorphine administered on a monthly basis for purposes of calculating the drug component under the OTP benefit, though we seek comment on whether this average typical dose (100 mg) is close to the dose for the monthly formulation of Brixadi that patients receive on average