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Curr Opin Cardiol 2007

Furthermore, multiple reports imply that cholinergic loss may be an early sign of cognitive decline in AD, and can therefore have a more crucial role in A depositions, Tau phosphorylation, and neuroplasticity (Terry and Buccafusco, 2003

For instance, sulfated glycosaminoglycans (GAGs) in the gut is necessary for preventing leaky gut and maintaining nutrient absorption, as well as regulating cholecystokinin and gastrin (intestinal hormones)

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It was registered at the US National Institutes of Health (ClinicalTrials.gov) #NCT01366859