After invasion into the host, mycobacteria induce NADPH oxidase 2 (NOX2) expression to generate superoxide radicals (O 2 ), which are then converted to more toxic hydrogen peroxide (H 2 O 2 ) by superoxide dismutase (SOD) and subsequently reduced to water and molecular oxygen by catalase [57, 58]
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While stratification of participants according to race or ethnic groups have not identified significant differences in the cardiovascular efficacy of GLP-1RAs, 69 given the under-representation of these populations in CVOTs, it is currently unclear whether GLP-1RAs reduce cardiovascular risk in specific race/ethnic groups (eg, black patients)
Vitamin D intake and season modify the effects of the GC and CYP2R1 genes on 25-hydroxyvitamin D concentrations