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If you are starting semaglutide for weight loss, you must choose the 0.25 mg pen

Semaglutide may reduce appetite enough that people unintentionally skip meals or eat extremely small portions

The same study also proved its safety for obese and overweight adults without diabetes, deeming it acceptable from both a patient and clinical perspective

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Very high baseline A1C and long-standing diabetes Pre-existing diabetic retinopathy or macular edema Concurrent insulin therapy Large and rapid A1C reductions over a short period Additional vascular risks such as high blood pressure, high cholesterol, kidney disease, or sleep apnea Improving glucose control remains important for long-term eye health