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The epigenetic change in PASMC led to the activation of HIF-1, which caused a proliferative and antiapoptotic phenotype (hypoxia-inducible factor-1)

Contributed reagents/materials/analysis tools: NSA HK MH MFH

Detoxification: Glutathione plays a key role in detoxifying the skin by eliminating toxins and waste products from the body

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In the last years, a link between gut microbiota composition and autoimmune diseases has been proven in murine models and hypothesized in humans owed to the interactions with both the innate and adaptive branches of immunity [179]