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We are seeing that if you do that approach, its safe, more patients are able to complete all the therapy lines, and we are noticing an increase in pathologic complete response rates. Pathologic complete response describes the absence of any detectable cancer cells in a tissue sample following a particular treatment

Noce A, Ferrannini M, Fabrini R, Bocedi A, Dess M, Galli F et al

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Types of chelating agents include: When treatment begins, doctors gradually increase the dose of chelating agents

This component accounted for 37% of the variance of changes in these subjective measures and was used as an index of NAL aversion (see Supplementary Table 1), where higher component scores were associated with more aversion