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doi: 10.3109/09513590.2014.943725 134 OrioFPalombaS

While preclinical studies and anecdotal evidence suggest potential benefits, the lack of comprehensive clinical trial data limits our understanding of its full therapeutic potential and possible side effects

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The safety profile appears favorable for extended use based on available data, though long-term studies specifically on oral formulations do not exist

Differential Calcium Independent Regulation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinases by Interleukin-1 and Transforming Growth Factor- in Peyronie's Plaque Fibroblasts