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The healthy heart has metabolic flexibility, enabling mitochondria to adaptively utilize different substrates depending on oxygen levels, substrate concentrations, and enzyme activity to produce ATP that meets cardiac needs, with fatty acids being the most productive substrate (Xu et al., 2018), though its exact therapeutic mechanism remains unclear

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Cognitive difficulties, often referred to as fibro fog, can impact the ability to focus, pay attention, and concentrate on mental tasks

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Exendin-4 Protects against Hyperglycemia-Induced Cardiomyocyte Pyroptosis via the AMPK-TXNIP Pathway