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Contraindications : Pregnant and breastfeeding women should avoid berberine due to safety concerns, though inositol has been studied in pregnancy for gestational diabetes

The positive trial data suggests that the pill could be an effective treatment for patients to transition to if they want to preserve their weight loss but don't want to take weekly injections long term

Accessed July 26, 2026

Corovie M, Milivojeric A, Simovic M, Banjanea K et al (2020) Enzymatically derived oil-based L-ascorbyl esters: synthesis, antioxidant, properties and controlled release from cosmetic formulation