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GLP-1 suppresses appetite in the brains hunger center (hypothalamus)

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A multicenter randomized controlled trial of a nutrition intervention program in a multiethnic adult population in the corporate setting reduces depression and anxiety and improves quality of life: the GEICO study

Furthermore, studies indicate that long-term chronic inflammation and excessive production of inflammatory mediators may trigger inflammatory processes, activating microglial cells in the brain, leading to dopaminergic neuronal degeneration and increasing the risk of Parkinsons disease (Marogianni et al., 2020)

However, its important to note that neither medication is FDA-approved for weight loss, though healthcare providers may prescribe them off-label for this purpose when clinically appropriate