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MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA- c) is a small peptide comprised of 16 amino acids, which is encoded by DNA not in the nucleus, but inside the mitochondrial genome, specifically inside the gene that encodes the mitochondrial 12S ribosomal RNA

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Front Endocrinol (lausanne) 10:389 Gerich JE, Lorenzi M, Bier DM, Schneider V, Tsalikian E, Karam JH et al (1975) Prevention of human diabetic ketoacidosis by somatostatin

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