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Transition metalbased carriers (e.g., MnO, Cu 2 , Fe 3 ) provide an additional layer of functionality, as they can both deplete intracellular GSH and generate reactive oxygen species, thereby amplifying oxidative stress within tumors

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APLB , ( B3), , , () 40 , , , , , 8809874682679 Water, Centella Asiatica Extract (29.2%), Butylene Glycol, Propanediol, Niacinamide (20 000 ppm), Glycerin, Diethoxyethyl Succinate, Panthenol, Sodium Hyaluronate, Allantoin, Glutathione (1 000 ppm), Sodium Polyacryloyldimethyl Taurate, Glyceryl Acrylate/Acrylic Acid Copolymer, Nelumbo Nucifera Extract, Artemisia Annua Extract, Oryza Sativa (Rice) Extract, Saccharomyces Ferment, Solanum Melongena (Eggplant) Fruit Extract, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Hydroiyzed Collagen, Squalane, Beta-Glucan, Ascorbic Acid, Dipropylene Glycol, Hippophae Rhamnoides Fruit Extract, Adenosine, Madecassic Acid, Asiaticoside, Asiatic Acid, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Glyceryl Stearate, Cholesterol, Styrene/Acrylates Copolymer, Cellulose Gum, Xanthan Gum, Inulin, Cellulose, Glucose, Fructose, Citric Acid, Disodium EDTA, Hydroxyacetophenone, 1,2-Hexanediol, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Sodium Citrate

Interestingly, BSO alone was insufficient to induce ferroptosis in MDA-MB-231 cells (Supplementary Fig