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doi: 10.3389/fmicb.2020.00090 74 HanLShuXWangJ

Recent regulatory guidance documents, such as the 2025 Australian Therapeutic Goods Administration (TGA) guidance on the quality of listed probiotic medicines and broader discussions on LBPs from 2020, underscore the necessity for strain-level identification, validated enumeration techniques, and explicit labeling of potency and storage conditions (570, 571)

Recent independent systematic reviews and meta-analyses support the use of meal replacement interventions and report larger weight loss after 1 year of follow-up with meal replacements compared to conventional weight loss diets [133,135]

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pylori infection, or stomach surgery can reduce absorption