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With an increase in the incidence of noncommunicable diseases (NCDs) such as diabetes, cardiomyopathies, cancers, and epilepsy, which are often associated with oxidative stress, people resort to the use of dietary supplements (known antioxidants) to prevent these diseases [2]

The transmembrane domain of GPER primarily binds ligands such as estrogen, initiating signal transduction

Potential Skin Cancer Risk Reduction (Preclinical/Mechanistic) Eumelanin is the skin's primary endogenous photoprotectant

In a melanoma mouse model, the LDHA inhibitor GSK2837808A improved the therapeutic effectiveness of adoptive T-cell therapy (ACT) [344]