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The glycolysis inhibitor 2-desoxy-D-glucose (2-DG) and costunolide showed similar effects in inhibiting the rate-limiting enzyme HK2, leading to decreased expression of HSC activation markers such as -SMA and collagen I
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HUBERMAN: And in addition to wanting to teach you about some of the biology of these peptides and how they work and what they're designed to do, as well as some of their potential therapeutic benefits under the right conditions, again, working with a really good board-certified physician and making sure that the sourcing is really clean
