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In DAPA-HF, the treatment benefit of dapagliflozin 10 mg in reducing the incidence of the primary composite endpoint was consistent in patients with type 2 diabetes mellitus [HR 0.75 (95% CI 0.63, 0.90)], and in patients with type 2 diabetes mellitus and metformin HCl as background therapy [HR 0.67 (95% CI 0.51, 0.88)]

doi:10.1038/ijo.2008.148 60

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