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To counteract potential protopathic or ascertainment bias, any instances of primary and secondary outcomes that manifested before the designated index date were disregarded, prompting a repeat of the PSM process
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In this Review, we present a comprehensive and clinically useful approach to cardiomyopathy related to anthracycline therapy, encompassing its epidemiology, definition, mechanisms, novel classifications, risk factors and patient risk stratification, diagnostic approaches (including imaging and biomarkers), treatment guidelines algorithms, and the role of new cardioprotective drugs that are used for the treatment of heart failure