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The lead postbiotics, AL0044 (garlic extract-derived) and AL0047 (senna leaf-derived), achieved TMA lyase inhibition comparable to that of the synthetic reference inhibitor FMC

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This stimulates NO production by endothelial NO synthase (eNOS) in cavernous arteries [4] Non-adrenergic non-cholinergic neurons (NANC) activate neuronal NO synthase (nNOS) [4] Nitric oxide then binds to guanylate cyclase in cavernous smooth muscle

Beneficial Effects of L-Carnitine Supplementation for Weight Management in Overweight and Obese Adults: An Updated Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials