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c f , Inactive analog KL7 (40, 100 M) and weak analog KL2 (100 M) showed minimal to no effect on ROS/RNS levels in infected ( c , d ) and uninfected ( e,f ) macrophages after 4 h ( c , e ) and 8 h ( d,f ) treatment

There may be decreased resistance and inability to localize infection when corticosteroids are used

A compromised intestinal lining allows bacterial endotoxins into systemic circulation, driving inflammatory cytokine production that worsens insulin resistance and ovarian function

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The Two-Tier Supplementation Framework Before I get into the specifics of B12 supplementation in the next section, I want to explain the broader framework I use for all post-weight-loss patients