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The gastrointestinal tract gradually adjusts to slower emptying, and patients learn to modify eating patternssuch as eating smaller, more frequent meals and avoiding trigger foodswhich reduces reflux frequency

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Our laboratory has recently synthesized a metabolically stable AngIV analog that acts by way of the hepatocyte growth factor (HGF)/c-Met receptor system (133136) to overcome the motor dysfunctions that follow 6-OHDA-induced lesions of the substantia nigra pars compacta in the rat (unpublished results)

The peptide activates the FAK-paxillin signaling pathway, which controls how fibroblasts migrate to injury sites