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In chronic wounds, there is excessive secretion of inflammatory mediators, such as cytokines and matrix metalloproteinases (MMPs), which degrade growth factors and the extracellular matrix (ECM), further impairing healing

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when it is inhibited by high levels of oxidative stress, mast cells fire uncontrollably and unpredictably

We use the differential equations for the rate of change of the number of living hepatic cells and the rate of change of the number of damaged cells from[10]