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GHK-Cu significantly reduced inflammatory cytokines TNF-alpha, IL-6, and IL-1beta, enhanced mucosal repair, and upregulated tight junction protein expression through inhibition of the SIRT1/STAT3 signaling pathway

Spatial transcriptomics combined with single-cell RNA sequencing identified high expression levels of ferroptosis-related genes, including TFRC, NCO4, and SLC3A2, in granulosa cells of patients with ovarian senescence, while GPX4 expression was notably low (Lin et al., 2023)

In summary, iron is vital for hemoglobin production and energy metabolism

For example, grape seed extract, applied to normal human melanocyte and dermal fibroblast cells, was shown to enhance skin youthfulness by stimulating collagen and elastin production (133)

The role of cardiolipin in promoting the membrane pore-forming activity of BAX oligomers