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VeterinarianVeterinarianExpert AnswerShots are usually injected subcutaneously (in the space underneath the skin before reaching the muscle) between the shoulder blades
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At the physiological phenotype level, CRISPRa has also been used to increase the transcription of obesity risk genes SIM1 and MC4R , and to successfully rescue haploinsufficient obesity in mouse modelswith the effects persisting up to 9 months post-treatment [80]
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