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In support of the two-pathways hypothesis, non-caloric sweeteners mediated responses differ from those elicited by natural sugars as they have a higher potency, a delayed on- and off-set, and a lower sweetness intensity (DuBois et al., 1991

44 Flumazenil may be considered for selected patients with HE and chronic liver disease

doi: 10.1038/nrc1143 27 TaniguchiRInoueASayamaMUwamizuAYamashitaKHirataKet al

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