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Semaglutides efficacy relating to body weight was also evident compared with sitagliptin, with greater proportions of participants achieving body weight loss of 5% (29% and 57% vs 7%, respectively) and 10% (7% and 19% vs 0%, respectively)

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Mol Neurobiol 54:44324451 Wang X et al (2023) Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation

This prevents small cosmetic changes from overshadowing the profound health benefits these medications deliver