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Laskaris et al., 2016

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A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group

For this reason, patients under semaglutide could benefit from this nutritional therapy, specifically those with more complicated metabolic profiles and who seek for substantial weight loss in the initial phase