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Interestingly, both p53 and FOXO control a distinct set of genes that are not targets of Nrf2 activity, even though all three factors induce HMOX1 expression and, therefore, Fe(II) storage and secretion, that plays a role in breast tumorigenesis, highlighting the role of antioxidants in cancer promotion 28

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meningitidis comes from studies conducted on single or co-cultured cell lines that only remotely mimic real in vivo conditions

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If vitamin deficiencies are suspected (particularly B12, zinc, or iron), discuss appropriate testing with your healthcare provider before considering supplements