Observational studies Most of the early observational evidence from case-control and nested case-control studies suggested either null or inverse associations between selenium exposure and risk of site-specific cancers (67)
Main documentation is based on in vitro and preclinical data A variety of microorganisms including bacteria (e.g., Clostridium difficile 157 ), archaea (e.g., Methanococcus jannaschii 158 ), fungi (e.g., Eremothecium ashbyii 159 , Saccharomyces cerevisiae 160 ) have a documented capacity to produce riboflavin at different levels 40,161 , although in general, under physiological conditions the microbial riboflavin production is very low (few g/L, or less, in culture media)
doi:10.1080/09546634.2022.2076418
232596711880454, High-Dose Vitamin c (PDQ)Health Professional Version - National Cancer Institute. Www.cancer.gov, 8 Feb
Of the 119 inter-molecular NOE restraints, only 20 NOEs could be assigned unambiguously (Supplementary Note 2)