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Similar to cagrilintide, pramlintide is primarily eliminated via the kidneys and, in a pharmacokinetic study in participants with type 1 diabetes, no statistically significant differences were noted in total (AUC 0- ) and peak ( C max ) exposure after administration of a single pramlintide 60 g dose in participants with mild, moderate or severe renal impairment compared with those with normal renal function, although inter-patient variability was high [20]

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The ratio of ruthenium released from the nanoparticles was calculated as the percentage of cumulative ruthenium in the dialysate relative to the total amount of ruthenium present in the nanoparticles

VPA is still one of the most widely used and effective antiepileptic drugs for most types of epilepsy (Campos et al

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimers disease-associated A oligomers