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49 mtDNA point mutations and deletions increase exponentially with age, disrupt the assembly of the oxidative phosphorylation complex, reduce adenosine triphosphate (ATP) and increase electron leakage, and form a vicious cycle of ROS-damage-ROS

Fat metabolism is being optimized at the cellular level

The gut-brain axis is sensitive to all of these inputs, and optimizing them creates conditions where a supplement has the best chance of producing its intended effects

Vitamin B12 Vitamin B12 (cobalamin) is an essential water-soluble vitamin required for red blood cell production, DNA synthesis, and neurologic function

Where the dullness is driven by lifestyle and environmental load sun, travel, stress glutathione supports the underlying biology of healthier-looking skin, paired with sun protection and appropriate topical or procedural care