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J Food Sci Technol 54:20502058 Cramer MN, Hieda M, Huang M, Moralez G, Crandall CG (2020) Dietary nitrate supplementation does not influence thermoregulatory or cardiovascular strain in older individuals during severe ambient heat stress

Figure 2 3.1 Activation of inflammatory signaling pathways Research indicates that increased intestinal permeability allows endotoxins such as LPS to enter the systemic circulation, where they trigger systemic inflammatory responses by activating the Toll-like receptor 4/nuclear factor kappa-light-chain-enhancer of activated B cells (TLR4/NF-B) inflammatory pathway

[DOI] [PubMed] [Google Scholar] 22.Waring WS, Stephen AF, Malkowska AM, Robinson OD