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Eva Carro led the 2009 study as a researcher at the Hospital Universitario 12 de Octubre and the Instituto de Salud de Charles III (ISCIII), a government research organization

And so doctors are increasingly prescribing the drug off-label, purely for its effect helping people lose weight

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A direct head-to-head, the SURMOUNT-5 trial (released 2025), confirmed tirzepatide outperformed semaglutide for weight loss in adults with obesity without diabetes