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doi: 10.3389/fendo.2021.646233 232 BejoyJFarryJMPeekJLCabatuMCWilliamsFMWelchRCet al

Physical activity represents a potent, evidence-based intervention for enhancing metabolic health through multiple mechanisms, including improved insulin sensitivity, glucose utilization, and cardiovascular function

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Theoretical interactions with insulin, exogenous GH, somatostatin analogues, glucocorticoids, thyroid hormone, and other GHS-R1a ligands are mechanistically plausible