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La activacin del eje GH/IGF-1 por CJC-1295, un anlogo de GHRH de accin prolongada, produce cambios en el perfil de protenas sricas en sujetos adultos normales
Therefore, in T1DM, because of the lack of portal insulin levels, the liver stops producing enough IGF-1, which is followed by a compensatory rise in GH levels
Studies in healthy elderly individuals showed that Sermorelin administration could increase GH and IGF-1 levels toward more youthful ranges, with associated improvements in body composition (increased lean mass, reduced abdominal adiposity), sleep quality (enhanced slow-wave sleep), skin thickness, bone density markers, and subjective energy and vitality