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This supplement is labeled gluten-free.

Pursuing this, we performed immunofluorescence staining and detected MOR + signals with a nerve fiber-like morphology in the DMV, which were not co-labeled with the neuronal nuclei (NeuN, a marker for neuron), glial fibrillary acidic protein (GFAP, a maker for astrocyte), ionized calcium-binding adapter molecule 1 (Iba1, a marker for microglia), or a ChAT-specific antibody (Supplementary Fig

Metabolic signaling pathways

By inhibiting NNMT, 5-Amino-1MQ prevents the methylation of nicotinamide, which thus remains available for recycling to NAD+ via the salvage pathway

ValentiLFracanzaniALDongiovanniPBugianesiEMarchesiniGManziniPet al