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We believe the proposed requirement that hospitals encode in the MRF the name of a senior hospital official as the attester appropriately strengthens the attestation and the reassurances it provides to MRF users and CMS by providing accountability at a senior management level for the accuracy and completeness of the data

While RCTs remain the gold standard for intervention assessment, observational studies provide complementary evidence, especially when using objective biomarkers such as serum Vitamin B12, MMA, and homocysteine