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If the Pen has been frozen, throw the Pen away and use a new Pen

As you lose weight, your resting metabolic rate decreases

Common side effects are gastrointestinal, and rare serious events include pancreatitis and gallbladder disease

Cocaine Only limited clinical evidence is available for GLP-1RAs in cocaine misuse: a small ( N = 13) proof-of-concept trial across 2 days showed that exenatide compared with placebo did not reduce the number of self-administered cocaine infusions 115 , while a case series of 3 individuals with cocaine-use disorder highlighted the feasibility and safety of using the same drug over 6 weeks, although no efficacy measures were reported 116

Some studies suggest that Tirzepatide might even surpass both Retatrutide and Semaglutide in terms of weight loss efficacy, making it a promising alternative