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By this point, many individuals on GLP-1 therapies achieve at least a 5% reduction in body weight

However, tirzepatide 5 mg produced greater weight loss (-7.8 kg vs -5.7 kg), so it is not a true equivalency

Assess patients who present with signs and symptoms of metabolic acidosis for ketoacidosis, regardless of blood glucose levels

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This faster regain could be because people using drugs dont need to consciously practise changing their diet to lose weight, so when they stop taking the medication, they might not have developed the practical strategies that could help them keep it off, said senior author and Oxford associate professor Dimitrios Koutoukidis in an official statement