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Notably, this study revealed that enzymatic antioxidants like catalase, Cu/Zn-SOD, and Mn-SOD did not correlate with any of the survival parameters

Indeed, carnitine even reduced lipid metabolism in red sea bream 15 , yellow catfish 24 and rainbow trout 25

Finally, searching for biomarkers to predict the efficiency of glutamine targeting, or metabolomic and proteomic approaches to identify metabolic compensation mechanisms, will significantly improve the efficacy of cancer treatment

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We studied expression of five enzymes involved in carnitine biosynthesis, namely 6- N -trimethyllysine dioxygenase (TMLD), 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH), serine hydroxymethyltransferase 1 & 2 (SHMT1 & 2) and -butyrobetaine hydroxylase (BBH) by real-time PCR in mice (C3H strain)