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10.3389/fendo.2019.00080 33 DepommierC.EverardA.DruartC.PlovierH.Van HulM.Vieira-SilvaS.et al (2019)

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Posttraumatic stress disorder-like induction elevates beta-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses

Metabolic improvements (blood sugar, weight loss, body composition) typically become evident at 6-12 weeks