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These agents mimic the bodys natural glucagon-like peptide-1 hormone, regulating blood glucose while promoting satiety and weight loss

According to the SUSTAIN 6 trial, the average increase in heart rate is between 2.75-3.2 beats per minute (bpm), which is clinically insignificant. While the average heart rate increase is between two and three beats per minute, some individuals have experienced an increase of up to 10 bpm in resting heart rate after administering a 1.5 mg dose of semaglutide

And the gastrointestinal side effects of semaglutide, particularly nausea and acid reflux, can make restful sleep difficult

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It works "pretty well in most people" for improving blood sugar, she said, but "for weight, there does seem to be a little bit more variation" in how well it helps people trim down