National Library of Medicine (DailyMed) Bacteriostatic Water for Injection, USP label DailyMed (2025) 2
Certain groups are at a higher risk of B12 deficiency, including the elderly because of reduced absorption due to decreased stomach acid
By inhibiting NNMT, it alters the balance of S-adenosylmethionine (SAM) and nicotinamide metabolism, affecting DNA methylation patterns and histone modifications
If your B12 is too high, check with your doctor to rule out liver disease, diabetes, leukemia, and other cancers
Secondly, B12 shots dont always resolve the underlying problem of deficiency, so theyre not the be-all and end-all when it comes to treating symptoms