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Occurred in 8.8% of participants on 9 mg and 20.9% on 12 mg, compared to 0.7% on placebo Dose-dependent (higher dose, higher risk) Generally described as mild Rarely led to discontinuation Why this matters: Dysesthesia was not reported in the Phase 2 trial
What this means in practice: If your prescription is for Ozempic (the diabetes-indication brand), you'll be eligible to switch to generic semaglutide once your dispensing pharmacy stocks it
Ozempic also carries an indication for reducing the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with type 2 diabetes and established cardiovascular disease
Alcohol can reduce the effectiveness of the medication and trigger side effects
Digestive system: increased satiety GLP-1 RAs increase satiety by inhibiting gastrointestinal motility [7]
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