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As outlined above in DFUs, chronic hyperglycemia impairs innate immune responses and vascular function, leading to inefficient pathogen clearance and prolonged inflammation

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The hormonal imbalances seen in females with PCOS are decreased follicle-stimulating hormone (FSH) and FSH/LH ratio, increase in the level of LH, fasting insulin, estrogen, free testosterone, and a mild increase in prolactin [4]

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