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Both effects were reduced by ferrostatin-1 treatment (Fig
For diclofenac, a significant decrease in activity in GSH conjugation of diclofenac 1,4-quinone imine is observed for variants hGSTP1-1*B (Val105/Ala114) and hGSTP1-1*C (Val105/Val114) (Dragovic et al.)
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Similar to natural drugs, many synthetic drugs have properties that enhance the GSH system and thus protect cells from oxidative damage
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