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For patients who struggle with reflux on either medication alone, the GLP-Squared combination (dual compound of semaglutide and tirzepatide, at $289/mo month-to-month, or from $249/mo on the 6-month plan for injection) may offer a different balance of GLP-1 and GIP receptor activation that some patients tolerate better
Change history 28 January 2026 This article has been retracted
In May 2023, Omada rolled out a specialized program for members taking GLP-1s featuring lifestyle change resources as well as community support
doi: 10.1161/CIR.0000000000000954
